Sebastian F. Winter, M.D. Ph.D.

Research Articles

 Karschnia, P., Kurz, S.C., Brastianos, P.K., Winter, S.F., Gordon, A., Jones, S., Pisapia, M., Nayyar, N., Tonn, J.C., Batchelor, T.T. and Plotkin, S.R., 2023. Association of MTHFR Polymorphisms With Leukoencephalopathy Risk in Primary CNS Lymphoma Patients Treated With Methotrexate-Based Regimens. Neurology.Impact factor 2023: 12.258
Karschnia, P., Arrillaga-Romany, I.C., Eichler, A., Forst, D.A., Gerstner, E., Jordan, J.T., Ly, I., Plotkin, S.R., Wang, N., Martinez-Lage, M. and Winter, S.F.,.. Dietrich, J. 2023. Neurotoxicity and management of primary and secondary CNS lymphoma after adoptive immunotherapy with CD19-directed CAR T-cells. Neuro-Oncology, p.noad118.Impact factor 2023: 15.9
Winter, H.E., Klapprott, F., Naanaa, M., Turk, A.M., Winter, S.F., 2022. Psychosocial Peer Mediation (PPM) as Sustainable Method for Conflict Prevention and Management among Refugee Communities in Germany. Conflict Resolution Quarterly, 39( 3), 195– 210. Impact factor 2021: 3.211
Winter, S.F., Klein, J.P., Vaios, E.J., Karschnia, P., Lee, E.Q., Shih, H.A., Loebel, F. and Dietrich, J., 2021. Clinical Presentation and Management of SMART Syndrome. Neurology, July 20, 2021; 97 (3).Impact factor 2020: 9.901Article featured in Spotlight on the July 20 Issue 2021
Winter, S.F., Forst, D.A., Oakley, D.H., Batchelor, T.T., Dietrich, J., 2021. Intracranial foreign body granuloma mimicking brain tumor recurrence: a case series. The Oncologist, May;26(5):e893-e897.Impact factor 2020: 5.550
Winter, S.F., Martinez-Lage, M., Clement, N.F., Hochberg, E.P., Dietrich, J., 2021. Fatal neurotoxicity after chimeric antigen receptor T-cell therapy: An unexpected case of fludarabine-associated progressive leukoencephalopathy. European Journal of Cancer, 144, 178–181.Impact factor 2020: 9.162
Winter, S.F., Vaios, E.J., Muzikansky, A., Martinez‐Lage, M., Bussière, M.R., Shih, H.A., Loeffler, J., Karschnia, P., Loebel, F., Vajkoczy, P. and Dietrich, J., 2020. Defining Treatment‐Related Adverse Effects in Patients with Glioma: Distinctive Features of Pseudoprogression and Treatment‐Induced Necrosis. The Oncologist, 25(8): e1221–e1232.Impact factor 2020: 5.550 Vaios, E.J., Winter, S.F., Muzikansky, A., Nahed, B.V. and Dietrich, J., 2020. Eosinophil and lymphocyte counts predict bevacizumab response and survival in recurrent glioblastoma. Neuro-Oncology Advances, 2(1), p.vdaa031.Impact factor: N/A (new journal). Karschnia, P., Batchelor, T.T., Jordan, J.T., Shaw, B., Winter, S.F., Barbiero, F.J., Kaulen, L.D., Thon, N., Tonn, J.C., Huttner, A.J. and Fulbright, R.K., 2020. Primary dural lymphomas: Clinical presentation, management, and outcome. Cancer, 126(12):2811-2820.Impact factor 2020: 6.860

Policy Research

 Winter S.F., Walsh D., Grisold W., Jordan J.T., Singhi P., Cross J.H., Guekht A., Hawrot T., Destrebecq F., Feigin V.L., Kariuki S.M. et al. Uniting for global brain health: Where advocacy meets awareness. Epilepsy & Behavior. 2023 Aug 1;145.
Winter, S.F. IGAP Unpacked: A Practical Guide to the World Health Organization’s Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders 2022 - 2031. International Bureau for Epilepsy, January 2023.
Winter, S.F., Walsh, D., Amos, A., Secco, M., Sofia, F., Baker, G.A. The WHO intersectoral global action plan and epilepsy cascade target: Towards a roadmap for implementation. Seizure: European Journal of Epilepsy,  103 (2022) 148–150.Impact factor 2020: 3.184
Winter, S.F., Angeler, D.G., Dawson, W.D., et al. Brain health-directed policymaking: A new concept to strengthen democracy. The Brookings Institution, November 2022.
Winter, S.F. and Winter, S.F., 2018. Human dignity as leading principle in public health ethics: a multi-case analysis of 21st century German health policy decisions. International journal of health policy and management, 7(3), p.210.Impact factor 2020: 5.007
The Division of Health Systems and Public Health, WHO Europe, 2015. Ambulatory care sensitive conditions in Germany. Copenhagen: WHO Regional Office for Europe; December 2015.

Review Articles


Winter, S.F., Vaios, E.J., Shih, H.A. et al. Mitigating Radiotoxicity in the Central Nervous System: Role of Proton Therapy.  Curr. Treat. Options in Oncol. (2023).Impact Factor 2022: 5.08
Vaios, E.J., Winter, S.F., Shih, H.A., Dietrich, J., Peters, K.B., Floyd, S.R., Kirkpatrick, J.P.,  Reitman, Z.J. Novel Mechanisms and Future Opportunities for the Management of Radiation Necrosis in Patients Treated for Brain Metastases in the Era of Immunotherapy. Cancers 2023, 15(9), 2432.Impact Factor 2022: 6.575
Winter, S.F., Jo, J., Schiff, D., and Dietrich, J., 2022. Central Nervous System Complications Among Oncology Patients. Hematology/Oncology Clinics of North America 36(1), pp.217-236.Impact factor 2021: 3.722
Winter, S.F., Vaios, E.J. and Dietrich, J., 2020. Central nervous system injury from novel cancer immunotherapies. Current Opinion in Neurology, 33(6), pp.723-735.Impact factor 2021: 5.710 Winter, S.F., Loebel, F., Loeffler, J., Batchelor, T.T., Martinez-Lage, M., Vajkoczy, P. and Dietrich, J., 2019. Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology. Neuro-oncology, 21(9), pp.1118-1130.Impact factor 2020: 12.300Editor’s Choice, September 2019 Issue Dietrich, J., Winter, S.F. and Klein, J.P., 2017, October. Neuroimaging of brain tumors: pseudoprogression, pseudoresponse, and delayed effects of chemotherapy and radiation. In Seminars in neurology (Vol. 37, No. 05, pp. 589-596). Thieme Medical Publishers.Impact factor 2019: 2.034 Winter, S.F., Loebel, F. and Dietrich, J., 2017. Role of ketogenic metabolic therapy in malignant glioma: a systematic review. Critical reviews in oncology/hematology, 112, pp.41-58.Impact factor 2019: 5.833 Winter, S.F., Santaguida, C., Wong, J. and Fehlings, M.G., 2016. Systemic and topical use of tranexamic acid in spinal surgery: a systematic review. Global Spine Journal, 6(3), pp.284-295.Impact factor 2019: 2.683 

Dissertation


Winter, S.F. , 2022. Characterization of cancer treatment-related neurotoxicity in patients with malignant glioma. Refubium, Freie Universitat Berlin Repository.

Textbooks


Dietrich, J. , Parsons, M.W., Wefel, J.S., and Winter, S.F.  (Editors). Neurotoxicity in Cancer Therapy. Springer Nature (forthcoming).

Book Chapters

 Winter, S.F. and Dietrich, J. , 2023. Neurological Complications of Radiation Therapies in Hematological Malignancies. In Oxford Textbook of NeuroHematology. In press at Oxford University Press.
Dietrich, J., Winter, S.F. and Parsons, M.W., 2019. Delayed Neurologic Complications of Brain Tumor Therapy. In Oncology of CNS Tumors (pp. 751-767). Springer, Cham.

Popular Scientific Writing


Angeler, D.G. ..Winter, S.F.,..et al. 2022. Building Brain Resilience: A Multi-Level Systems Approach. Psychiatric Times.
Eyre, H., Benentt, V., Winter, S.F., Freeman, M., and Hynes, W., 2022. Investing in the brain...to strengthen democracy. The RSA.
Eyre, H. ,...Winter, S.F.,..et al. 2022. Brain Capital: An Emerging Investment Opportunity. Psychiatric Times.

Selected Citable Abstracts

 Winter, S.F., Acevedo, K., Acevedo, C. et al. Leveraging Policy Frameworks for Epilepsy Advocacy in Latin America: An International Bureau for Epilepsy and Chilean League Against Epilepsy PAHO/WHO Collaborating Centre Multi-Stakeholder Workshop. AES 2023. 
Vaios, E., Shenker, R., Hendrickson, P., Wan, Z., Niedzwiecki, D., Winter, S.F., Dietrich, J., Salama, A., Clarke, J., Allen, K. and Mullikin, T., 2023. RADT-15. INTRACRANIAL OUTCOMES OF DUAL IMMUNE-CHECKPOINT INHIBITION AND SRS COMBINATION IN PATIENTS WITH MELANOMA AND NSCLC BRAIN METASTASES. Neuro-Oncology, 25(Supplement_5), pp.v51-v51.
Karschnia, P., Arrillaga-Romany, I., Eichler, A., Forst, D., Gerstner, E., Jordan, J.T., Ly, I., Plotkin, S.R., Wang, N., Martinez-Lage, M. , Winter, S.F., et al. 2023. CTIM-38. NEUROTOXICITY AND MANAGEMENT OF PRIMARY AND SECONDARY CNS LYMPHOMA AFTER ADOPTIVE IMMUNOTHERAPY WITH CD19-DIRECTED CAR T-CELLS. Neuro-Oncology, 25(Supplement_5), pp.v71-v71.
Karschnia, P., Traub, B.L., Doubrovinskaia, S., Richter, B., Seidel, S., Kuschel, L., Hinz, F., Rejeski, K., Winter, S.F., Müller, K. ,Quach, S., et al. 2023. BIOM-64. A PROGNOSTIC SCORING SYSTEM FOR IMMUNODEFICIENCY-ASSOCIATED PRIMARY CNS LYMPHOMAS: AN INTERNATIONAL MULTI-CENTER STUDY. Neuro-Oncology, 25(Supplement_5), pp.v19-v19.
Vaios, E.J., Shenker, R.F., Hendrickson, P., Wan, Z., Niedzwiecki, D., Winter, S.F., Dietrich, J., Salama, A.K.S., Clarke, J., Allen, K.J. and Mullikin, T.C., 2023. Intracranial Control with Combined Dual Immune-Checkpoint Blockade and SRS for Melanoma and NSCLC Brain Metastases. International Journal of Radiation Oncology, Biology, Physics, 117(2), pp.S171-S172.
Karschnia, P., Kurz, S.C., Brastianos, P.K., Winter, S.F., Gordon, A., Jones, S., Pisapia, M., Nayyar, N., Tonn, J., Batchelor, T. and Plotkin, S.R., 2023. MTHFR polymorphisms and neurotoxicity and overall survival after methotrexate-based therapy in primary CNS lymphoma. Journal of Clinical Oncology 41, no. 16_suppl (June 01, 2023) 2079-2079.
Winter, S.F., Gardner, M., Parsons, M., Grassberger, C., Bussière, M., Ehret, F., Kaul, D., Boehmerle, W., Endres, M., Shih, H. and Dietrich, J., 2022. RADT-23. MODALITY-SPECIFIC CNS INJURY FOLLOWING PROTON VS PHOTON BEAM RADIOTHERAPY IN GLIOMA. Neuro-Oncology, 24(Supplement_7), pp.vii54-vii54.
Gardner, M., Winter, S.F., Dietrich, J. Gerstner, E., Sherman, J., Shih, H., Parsons, M.W. NCOG-09. RADIATION INDUCED CEREBRAL VOLUME LOSS AND CEREBROVASCULAR DISEASE RISK IN SURVIVORS OF GRADE 2 AND 3 GLIOMAS. Neuro-Oncology, 24(Supplement_7), pp.vii198–vii199.
Winter, S.F., Gardner, M., Parsons, M.W., Grassberger, C., Bussière, M., Kaul, D., Boehmerle, W., Endres, M., Shih, H.A., and Dietrich., J. P03.05.A Radiation-induced leukoencephalopathy (RIL) in glioma: unique injury dynamics following proton vs photon beam radiotherapy.  Neuro-Oncology, Volume 24, Issue Supplement_2, September 2022.  EANO 2022.
Vaios, E.J., Shenker, R., Hendrickson, P., D’Anna, R., Niedzwiecki, D., Carpenter, D., Floyd, W., Winter, S.F., Dietrich, J. Floyd, S.,  Kirkpatrick, J., Mullikin, T., Allen, K., Salama, A., Clarke, J., Reitman, Z. MMAP-07 IMPACT OF SINGLE AND DUAL IMMUNE CHECKPOINT BLOCKADE ON RISK OF RADIATION NECROSIS AMONG PATIENTS WITH BRAIN METASTASES TREATED WITH STEREOTACTIC RADIOSURGERY, Neuro-Oncology Advances, Volume 4, Issue Supplement_1, August 2022, Page i16. 
Winter, S.F., Klein, J., Vaios, E., Loebel, F. and Dietrich, J., 2021. Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Series (4314). Neurology, 96(15 Supplement)
Winter, S.F., Vaios, E., Muzikansky, A., Bussière, M.R., Shih, H.A., Martinez-Lage, M., Loebel, F., Vajkoczy, P. and Dietrich, J., 2019. Treatment-related adverse effects in patients with brain cancer: identification of distinctive features for pseudoprogression and treatment-induced necrosis. (S30. 003). In AAN 2019 Annual Meeting. Vaios, E., Winter, S., Muzikansky, A., Nahed, B. and Dietrich, J., 2018. Circulating blood cell counts as potential biomarkers of outcomes in recurrent glioblastoma patients treated with bevacizumab: hout-15. Neuro-oncology, 20. Winter, S.F., Vaios, E.J., Muzikansky, A., Bussière, M.R., Shih, H.A., Martinez-Lage, M., Loebel, F., Vajkoczy, P. and Dietrich, J., 2018. P01. 105 Clinical and imaging features of pseudoprogression in malignant glioma. Neuro-oncology, 20(suppl_3), pp.iii255-iii255. EANO 2018. Winter, S.F., Löbel, F., Vaios, E.J., Bertalan, M.S., Bussière, M., Shih, H.A., Muzikansky, A., Martinez-Lage, M., Vajkoczy, P., Dietrich, J., 2018. Clinicoradiographic key features of biopsy-proven treatment-induced necrosis in patients with malignant glioma. (P057). In DGNC 2018 Annual Meeting.  Loebel, F., Winter, S.F., Onken, J., Cahill, D., Koch, A. and Dietrich, J., 2017, November. Molecular and genetic analysis identifies idh mutation as a key factor of long-term survival in glioblastoma patients. In SNO 2017 Annual Meeting. Wefelmeyer, W., Barnes, S., Winter, S.F., Burrone, J., Keller, G., Keck T., (2013). Exploring experience-dependent intrinsic and synaptic plasticity in the adult visual cortex. In BNA 2013 Festival of Neuroscience.

Media Recognition


Historic Epilepsy Workshop Meeting Held [Histórica reunión de trabajo por la epilepsia.] By Liga Chilena Contra la Epilepsia, 2023.
Are Mental Factors Contributing to an Erosion of Democracy? It’s time for brain health-directed policymaking. By Nadine Kabbani, Psychology Today,  2023
Brain health-directed policymaking: a new concept to strengthen democracy. EMEA Press, 2022
Wann dürfen wir wieder raus? Die Corona-Maßnahmen und ihr unabsehbares Ende. By Alexander Mäder, RiffReporter, 2020
How the keto diet could help cancer patients fight back with food, Miriam Kalamian, 2017 Ketogenic Diet May Affect Glioma Outcomes. By Brielle Urciouli, CURE Magazine, 2017
Ketogenic Diet May Positively Affect Patients with Glioma. By Brielle Urciouli, Oncology Nursing News, 2017 

Memberships & Peer Review 


Member:Society for Neuro-Oncology (SNO)American Academy of Neurology (AAN)European Association of Neuro-Oncology (EANO)Studienstiftung des Deutschen Volkes (SDV) ILAE Global Advocacy Council ILAE Global Health Task ForceILAE Research and Innovation TaskforceOneNeurology Partnership
Peer Reviewer:Neurology (Official Journal of AAN)Public Health Panorama ( Official Health Journal of WHO Europe) Conflict Resolution Quarterly (Official Journal of the Association for Conflict Resolution)OncotargetTherapeutic Advances in Medical OncologyJ Neurochemical Research
Scientific Advisory Board:Artificial Intelligence in Chronic Pain (AICP) Foundation